Lesson 6 – Toll Like Receptors (TLRs) exam

Welcome to your Lesson 6 - Toll Like Receptors (TLRs) exam

1. Structures of the Toll-like receptor family and their ligand complexes.
2. Chicken toll-like receptors and their significance in disease resistance.
3. Breeding for disease resistance in farm animals and poultry.
4. Importance of toll-like receptors in bovine innate immunity.
5. TLR molecules recognising nucleic acids or nucleotides derivatives
are positioned at
6. TLR molecules recognising lipid or protein ligands are positioned at
7. The first identified and probably best studied TLR in mammals is of
8. Toll gene was first identified in
9. TRIF stands for TIR domain containing adaptor protein inducing
interferon
10. Which regions of TLR molecules possess a conserved domain similar
to that of interleukin (IL)-1 and therefore called Toll/IL-1 receptor
(TIR) domain
11. The nuclear regions of TLR molecules possess a conserved domain
similar to that of
12. Toll gene was first identified in .
13. PAMP stands for .
14. TLRs are also known as receptors
15. The ectodomain of TLRs contains a region rich in residues
16. TLR signalling can be of  and   pathways
17.  The cytoplasmic regions of TLR molecules possess a conserved domain
similar to that of interleukin (IL)-1 and therefore called domain.
18. TLR molecules recognising are positioned at the
cell surface, whereas those recognising are positioned at endosomes.
19. TRIF stands for
20. Functions of TLR
21. Write short notes on TLR polymorphisms in domestic animals
22. Describe in detail about the structure of TLRs
23. Write a note on TLR in domestic animals
24. Explain the role of TLRs in animal reproduction
2 TLR molecules recognising nucleic acids or nucleotides derivatives are
positioned at the cell surface, whereas those recognising lipid or
protein ligands are positioned at endosomes.
26. The first identified and probably best studied TLR in mammals is of
Murine TLR4.
27. The endo-domain of TLRs contains a region rich in leucine residues
28. TLR signalling can be of MyD88-dependent and TRIF pathways.
29. 5 The ectodomain of TLRs contains a region rich in tryptophan residues
30. The nuclear regions of TLR molecules possess a conserved domain
similar to that of interleukin (IL)-1 and therefore called Toll/IL-1
receptor (TIR) domain.
31. TRIF stands for TIR domain containing adaptor protein inducing
interferon α.