Lesson 6 – Antigen and Antibody Interactions exam

Welcome to your Lesson 6 - Antigen and Antibody Interactions exam

1. Agglutination reaction is more sensitive than precipitation for the
detection of
2. Precipitation reaction is relatively less sensitive for the detection of

3. In which of the following case a large lattice is formed?

4. Precipitation reaction can be converted to agglutination reaction by
coating soluble antigen with

5. The bonds involved in antigen and antibody interactions are

6. Clearance of antigens by antibodies involve

7. The ability of antigen to stimulate the antibody production is called as
8. Class switching of immunoglobulins occurs

9. The intermolecular forces which contribute to the interaction between
antigen and antibody
10. The affinity constants of an antigen and antibody interaction cannot
be measured by
11. Antigen and antibody interactions lead to

12. Junctional diversity affects primarily the amino acid sequence in
13. Isotype switching and somatic recombination process causes .
14. Each B-cell productively rearranges a single H and L chain allele and
it exhibits the phenomenon of .
15. The proper joining of one VL to one JL is regulated by .
16. Isotype switching increases the of immunoglobulin classes
17. The immunoglobulin isotype is determined by the .
18. region of the antibody molecule which contributes the
affinity for antigen
19. A large number of are required to form a strong AgAb interaction
20. Number of determines the antibody valency
21. The lack of agglutination at high concentration of is called
as .
22. is better measure of binding capacity of antibody.
23. occurs when an antibody binds to a different-butsimilar antigen than the one for which it was raised;
24. describes how strongly a single antibody binds a given
antigen, while describes the binding of a multimeric
antibody to multiple antigens.
25. can differentiate between IgM and IgG
antibodies, thus determining the stage of the infection.
26. reactions produce visible aggregates of antibodyantigen complexes when antibodies or antigens are conjugated to a
carrier.
27. is a quantitative technique that measures serum
concentration of antigens, antibodies, and allergens
28. Affinity
29. Affinity maturation
30. Non-covalent bonds
31. Electrostatic bonds
32. Van der Waals bonds
33. Precipitation reaction
34. Radioimmunoassay (RIA)
35. Complement fixation
36. Western blotting
37. List out the types of antigen and antibody interactions in detail.
38. Enumerate the various types of non-covalent bonds between antigen
and antibody.
39. Agglutination requires complement activation and the production of
chemotactic factors
40. Cross-reaction is the result of epitopes common between two different
antigens.
41. Antigen-antibody reactions occur via covalent bonds and they are
irreversible.
42. Number of epitope on an antigen is known as its valency.
43. The presence of agglutination at low concentrations of antibodies is
called as prozone effect.
44. Antigens are soluble molecules and larger in size are necessary for
precipitation reactions.
45. The principle of competitive binding is prerequisite for complement
fixation test.
46. Western Blot technique generally contains SDS-PAGE analysis for
quantification.
47. The most crucial element of the detection strategy in ELISA is mainly a
specific antibody-antigen interaction.
48.Cross reactivity is the ability of paratope to react with specific epitope.