Lesson 5 – Bovine Lymphocyte Antigen (BoLA) and Buffalo Lymphocyte Antigen (BuLA) exam

Welcome to your Lesson 5 - Bovine Lymphocyte Antigen (BoLA) and Buffalo Lymphocyte Antigen (BuLA) exam

1. Mapping MHC Genes in River Buffalo.

2. Selection for disease resistance in dairy cattle

3. Future applications of Bovine Lymphocyte Antigen (BoLA) and Buffalo
Lymphocyte Antigen (BuLA).

4. How will you breed dairy cattle with disease resistance? Explain with
the most common disease encountered in your region.

5. CD4 T cells are generally restricted by

CD-1

MHC Class-I

MHC Class-II

β2 Microglobulin

6. Both class I and class II MHC molecules present antigens to T cells.
Class I molecules present processed _______ antigen, while class II
molecules present processed _______ antigen to T cells,
respectively.

Endogenous and exogenous

Exogenous and endogenous

Viral and bacterial

Allo- and auto

7. Allelic forms of MHC genes are inherited in linked groups as

Haplotype

Combined genotype

Co-dominant inheritance

Quantitative inheritance

8. Name of the rhesus MHC Class I molecules found in placenta

HLA

HLAG

HLA-G

Mamu-AG

9. The bovine MHC genes are referred to as

10. The MHC of buffalo is known as

11. The BoLA complex is located on chromosome of cattle and 2nd
chromosome of buffalo.

12. BoLA class II genes that are most studied and found to be
polymorphic are genes.

13. Write short notes on MHC class I antigens.

14. Association of MHC with disease resistance and productivity

15. Future applications of BoLA

16. Write an essay on Genomic Organization of the MHC Region

17. How will you characterize BoLA molecules?

Time is Up!